Plant Reactome: a knowledgebase and resource for comparative pathway analysis
نویسندگان
چکیده
منابع مشابه
Plant Reactome: a resource for plant pathways and comparative analysis
Plant Reactome (http://plantreactome.gramene.org/) is a free, open-source, curated plant pathway database portal, provided as part of the Gramene project. The database provides intuitive bioinformatics tools for the visualization, analysis and interpretation of pathway knowledge to support genome annotation, genome analysis, modeling, systems biology, basic research and education. Plant Reactom...
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The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations-an extended version of a classic metabolic map, in a single consistent data model. Reactome functions both as an archive of biological processes and as a tool for discovering u...
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Nicolas Tsesmetzis,a Matthew Couchman,a Janet Higgins,a Alison Smith,b John H. Doonan,c Georg J. Seifert,c Esther E. Schmidt,d Imre Vastrik,d Ewan Birney,d Guanming Wu,e Peter D’Eustachio,e,f Lincoln D. Stein,e Richard J. Morris,a Michael W. Bevan,c,1 and Sean V. Walsha,1 a Department of Computational and Systems Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom b Department of Metabo...
متن کاملReactome: a knowledgebase of biological pathways
Reactome, located at http://www.reactome.org is a curated, peer-reviewed resource of human biological processes. Given the genetic makeup of an organism, the complete set of possible reactions constitutes its reactome. The basic unit of the Reactome database is a reaction; reactions are then grouped into causal chains to form pathways. The Reactome data model allows us to represent many diverse...
متن کاملReactome Pathway Analysis
2 Pathway Enrichment Analysis Enrichment analysis is a widely used approach to identify biological themes. Here, we implement hypergeometric model to assess whether the number of selected genes associated with reactome pathway is larger than expected. We also implement a category net model for viusalization. • Hypergeometric model Hypergeometric model was implemented to assess whether the numbe...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2019
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkz996